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Non-Invasive Prenatal Testing & Anxiety

Prenatal Testing

Disclaimer: Elise Ho, aka “Dr. Ho” is a Holistic Health & Life Coach. Dr. Ho is NOT a medical doctor, licensed therapist, lawyer, or a bevy of other things. Products or services that Dr. Ho believes in are the only ones that she recommends. Dr. Ho may receive compensation, product, or an affiliate commission on anything you see on this site. This is a personal Website solely reflecting Dr. Ho’s personal opinions. Statements on this site do not represent the views or policies of any organization with which I may be affiliated.

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The Science Behind NIPT: How Non-Invasive Prenatal Testing Works


Non-Invasive Prenatal Testing (NIPT) is an advancement in prenatal care. It has changed how we  assess the health of an unborn child.  The testing offers a non-invasive, safe, and highly accurate method for detecting chromosomal abnormalities. As well, it can detect other genetic conditions. This is unlike traditional prenatal screenings. Traditional screening may involve invasive procedures. As well, they carry certain risks. In this article we will explore the science behind NIPT. 


Understanding Fetal DNA in Maternal Blood


The key to NIPT lies in the presence of fetal DNA in the mother’s bloodstream. During pregnancy, a small fraction of the baby’s DNA is released into the mother’s bloodstream. This happens through a natural process called “cell-free fetal DNA” (cffDNA) shedding. The phenomenon occurs as a result of the breakdown of fetal cells and placental tissue.

While the majority of the DNA in the mother’s bloodstream is her own, the cffDNA carries genetic information from the developing fetus. This unique characteristic allows scientists and healthcare professionals to analyze the fetal DNA present in maternal blood samples.

The NIPT Process


  1. Blood Sample Collection: The first step in a NIPT test from London pregnancy clinic. or wherever you have chosen. is the collection of a maternal blood sample. This sample contains a mixture of the mother’s own DNA and the cffDNA from the fetus.
  2. Isolation of Fetal DNA: In the laboratory, specialized techniques are employed to isolate and separate the cffDNA from the maternal DNA. This is a crucial step to ensure the accuracy of the test. For this reason, we are able to achieve specific analysis of the fetal DNA.
  3. Genetic Analysis: Once the fetal DNA is isolated, it undergoes genetic analysis. This analysis typically focuses on specific chromosomal regions of interest. For example, NIPT primarily screens for common abnormalities. Some of the tests also include assessments for other genetic conditions, such as microdeletions and sex chromosome disorders.
  4. Data Interpretation: The genetic information obtained from the analysis is carefully interpreted. The concentration is to determine whether abnormalities or genetic variations are present in the fetal DNA. Prior to meeting with the parents, the provider will review the results.
  5. Result Communication: The healthcare provider reviews the results with the expectant parents. An important focus is explaining the findings and what they will mean for the family and the child. It’s important to note that NIPT provides risk assessment. It does not provide a definitive diagnosis. Further diagnostic testing is recommended in cases of high risk.

The Accuracy of NIPT


One of the most significant advantages of NIPT is its high accuracy in detecting chromosomal abnormalities and genetic conditions. Studies have shown that it has a sensitivity rate of over 99% for conditions like Trisomy 21.  Consequently, it is an extremely reliable screening method.

However, it’s essential to understand that NIPT is a screening test. It is not a diagnostic test. It can provide a highly accurate risk assessment. However, a definitive diagnosis  requires additional diagnostic procedures.



Non-Invasive Prenatal Testing is a remarkable advancement in the field of prenatal care. It offers parents a low risk, highly accurate means of assessing their baby’s health. Isolating and analyzing fetal DNA present in maternal blood provides valuable insights. This includes insight into the risk of chromosomal abnormalities and other genetic conditions.

The science behind NIPT has improved the accuracy of prenatal screening. Above all, it has reduced the need for invasive procedures that carry potential risks. Consequently, it is the preferred choice for expectant parents. 

Read on for Practical Tips for Postpartum Self-Care. 

Please use the comment section below to share your tips, questions, and/or thoughts about this post.

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Naturally Yours,
Elise Ho
Ph.D., D.N. Psych.
Behavioral & Mental Health Specialist

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About The Author

Dr. Elise Ho

Dr. Elise Ho

Dr. Elise Ho is a Holistic Health & Life Coach with a special interest in emotional health, life alignment, and energy flow.

Elise will partner with you to align your mindset, your energy, your home and your career so that you can live your life's desire with freedom and love.

Elise offers 30 years of experience and multiple certifications and degrees including a Ph.D. in Natural Health and a doctoral degree in Naturopathic Psychology.